No, party poppers are strictly single-use devices. Here's why reuse is impossible and dangerous:
Party poppers contain a small explosive charge (typically a friction-sensitive compound like silver fulminate or a tiny gunpowder charge) that ignites when the string is pulled. This combustion propels confetti or streamers. Once fired, the chemical reaction is complete—the charge is spent.
Bottom Line: Buy new poppers for each celebration. They're inexpensive, and the safety risk of reuse far outweighs any savings.