Operation (1965, Milton Bradley) premise:
You are a surgeon operating on Cavity Sam, a patient with 12 comic ailments. Using metal tweezers, remove each plastic piece from its cavity without touching the metal rim. Touch the rim → buzzer sounds, Sam's nose lights up red, you fail that piece.
Modern Versions: Operation: Star Wars (BB-8), Operation: Disney, Operation: Pet Scan (vet), Operation: Silly Skill Game (no money, just cards). Same core mechanic.