Absolutely. Games have no gender. Zwinky Cuties—a browser-based avatar/dress-up game popular in the late 2000s—was marketed toward girls but enjoyed by players of all genders.
Enjoyment of creativity, self-expression, social interaction, or casual gameplay is universal. Encouraging children to explore interests regardless of marketing labels fosters healthier development and breaks down arbitrary stereotypes.
Note: Zwinky/Cuties services were discontinued years ago; this applies to similar games (e.g., Roblox, Animal Jam, modern avatar creators).