Can You Play Metroid II in Color on Game Boy Advance? No - Hardware Limitation

No. Metroid II: Return of Samus is a monochrome Game Boy game. The Game Boy Advance can play it via the cartridge slot (on GBA, GBA SP, or Game Boy Player), but it will display in black and white—hardware cannot add color to original Game Boy software.

Ways to Experience Metroid II in Color

• Emulators: PC/mobile emulators (e.g., VisualBoyAdvance, mGBA) offer colorization filters.
• Remake: Metroid: Samus Returns (Nintendo 3DS) is a full 3D color remake with new mechanics.

So while the GBA hardware won't colorize the original cartridge, you have modern alternatives.