Wrong Game Version/Region: Codes are specific to exact release (e.g., NTSC-U v1.0 vs v1.1, PAL, Greatest Hits). Match Product Code (SLUS-xxxxx / SLES-xxxxx).
Master Code Missing: Most devices require a "Master Code" (M) / "Enable Code" entered first — hooks the cheat engine. Without it, nothing activates.
Code Format Error: Typos (O vs 0, I vs 1), wrong code type (RAW vs ARv1/2/3 vs CB), line breaks missing.
Game Updated / Patched: Modern consoles (PS3/360/Wii/PS4/5) patch games — offsets shift, codes break.
Anti-Cheat / Integrity Checks: Game checksums RAM → detects modification → crashes, freezes, or disables cheats.
Hardware Incompatibility: Using PS2 codes on PS3 BC, or AR Max on slim PS2 (different memory map).