No. Super Mario Galaxy (2007) is a **Wii exclusive**. It cannot run on Nintendo DS / DS Lite / DSi / 3DS.
| Factor | Wii | Nintendo DS |
|---|---|---|
| CPU | PowerPC "Broadway" @ 729 MHz | ARM9 @ 67 MHz + ARM7 @ 33 MHz |
| GPU | ATI "Hollywood" — 3D, shaders, TEV | 2D sprite engine + basic 3D (no shaders) |
| RAM | 88 MB (24 + 64) | 4 MB + 4 MB |
| Storage | 4.7 GB DVD (streaming assets) | 128–512 MB Cartridge |
| Controls | Wii Remote + Nunchuk (IR, motion) | D-pad, Touchscreen, Mic, Buttons |
The game **requires** Wii Remote pointer for star cursor, motion for spin/shake, and IR for pulling stars. DS has **no equivalent**.
Play Galaxy On: Wii, Wii U (back compat), **Switch (Super Mario 3D All-Stars, limited 2020–2021)**, or **PC via Dolphin Emulator** (4K, 60 fps, mouse/keyboard or controller).