Can You Play Nintendo DS Games on Wii? No – Completely Different Architectures

No. The Wii (home console) and Nintendo DS (handheld) have completely different architectures—CPU, GPU, memory, media (disc vs. cartridge), inputs (Wii Remote vs. dual screens/touch). No hardware or software compatibility exists.

Options for DS games:

• Original DS/DS Lite/DSi/3DS family
• PC/mobile emulation (DeSmuME, melonDS, DraStic) — legal with owned carts
• Wii U Virtual Console (select DS titles, e.g., Mario Kart DS, Pokémon Ranger)