Is There a Family Guy Game on Nintendo DS?

No, there is no official Family Guy game for the Nintendo DS.

The franchise has seen releases on other platforms:

• Family Guy: Video Game! – Xbox 360, PlayStation 3, Windows
• Family Guy: Back to the Multiverse – Xbox 360, PlayStation 3, Windows, Wii
• Family Guy: The Quest for Stuff – Mobile devices (iOS/Android)

Despite the series' popularity, no title was ever developed specifically for the DS hardware.