Absolutely not. The Nintendo 3DS and Game Boy Advance are separated by two hardware generations and incompatible architectures.
| Spec | Game Boy Advance (2001) | Nintendo 3DS (2011) |
|---|---|---|
| CPU | ARM7TDMI @ 16.78 MHz | ARM11 MPCore @ 268 MHz (dual) + ARM9 @ 134 MHz |
| RAM | 256 KB WRAM + 96 KB VRAM | 128 MB FCRAM + 6 MB VRAM |
| GPU | None (software rendering) | PICA200 (400 MHz, shaders, 3D) |
| Media | 32 MB GBA Cart (max) | 2–8 GB 3DS Cart (proprietary) |
| Screen | 2.9" 240×160 | 3.53" 800×240 (3D) / 320×240 (2D) |
Install TWiLight Menu++ (custom firmware) → Run GBA ROMs via gbARunner2 (hardware-assisted) or mGBA (software). Requires CFW (Luma3DS).