Can R4i / R4 DS Cards Connect to Wii? No – They're DS-Only.

Hardware Incompatibility

R4i and R4 DS cards are designed exclusively for Nintendo DS/DS Lite/DSi/3DS (in DS mode). They cannot connect to, function on, or interact with a Wii in any way.

Key Facts

• R4 cards use the DS cartridge slot (SLOT-1) – physically and electrically incompatible with Wii's disc drive / SD slot / USB ports.
• The Wii does not support any flash cartridges – no homebrew loader runs DS flash carts on Wii.
• No adapter, cable, or software bridges DS flash carts to Wii.

What R4 Cards *Do* Work On

• Nintendo DS / DS Lite (original R4)
• DSi / DSi XL (R4i, R4i Gold, R4i SDHC, Acekard 2i, etc.)
• 3DS / 2DS / New 3DS (in DS backward compatibility mode – limited to DS homebrew/ROMs, not 3DS ROMs)

If you want homebrew on Wii, look into Letterbomb (softmod) or ModMii guide for installing Homebrew Channel, USB loaders, and emulators natively on Wii.