Guitar Hero vs. Rock Band Instruments on PS2: Not Compatible

No, you cannot use Guitar Hero guitars for Rock Band on PS2.

Why They're Incompatible

• Different button layouts: Guitar Hero uses 5 fret buttons; Rock Band uses 6 (including the solo buttons).
• Different hardware protocols: Each series communicates with the console differently.
• Software locks: Rock Band does not recognize Guitar Hero controllers.

Even though they look similar, they function as completely different instruments. You must buy Rock Band-branded guitars, drums, and microphone to play Rock Band on PS2.