A PS/2 mouse connects via a 6-pin mini-DIN connector (purple port) on legacy motherboards. Standard on PCs from ~1990–2005, replaced by USB.
Use a PS/2-to-USB adapter ($3–$5) if you have a vintage mechanical keyboard/mouse. For gaming, any modern USB optical/laser sensor (1000+ Hz polling) outperforms PS/2. PS/2 persists only in industrial/KVM/legacy installs.