Can You Play Xbox 360 Games on PS2? No.

No. Xbox 360 and PlayStation 2 are fundamentally incompatible:

• CPU/GPU architecture: PowerPC tri-core vs. Emotion Engine.
• Disc format: DVD-DL vs. DVD-ROM with different encryption.
• OS and API incompatibility.

Play Xbox 360 games on Xbox 360, Xbox One/Series X|S (via backward compatibility), or PC (via emulation).