Most Popular PS3 Games in the US: Top Titles by Sales and Acclaim

No definitive "most popular" list exists—popularity measured by sales, player activity, critical acclaim, cultural impact, all with limitations.

Games consistently high in sales/popularity for PS3:

• Grand Theft Auto V: Best-selling ever, massive PS3 hit.
• The Last of Us: Critically acclaimed post-apocalyptic survival classic.
• Uncharted 2: Among Thieves: Action-adventure masterpiece, huge success.
• Call of Duty: Modern Warfare 3: Popular CoD entry, strong multiplayer.
• Minecraft: Sandbox hit across platforms, including PS3.
• Red Dead Redemption: Western with strong following.
• Mass Effect 2: Acclaimed sci-fi RPG hit.
• God of War III: Considered series best.
• LittleBigPlanet 2: Creative platformer hit with critics/players.
• Fallout 3: Popular post-apocalyptic RPG.

Note: Not exhaustive; research genres/time periods for personal appeal.