The red SYNC button (front SD card slot flap) pairs Wii Remotes. If it fails, the issue is usually debris, a worn tactile switch, or Bluetooth module failure.
If cleaning fails, the Bluetooth Module (small daughterboard near front) is likely faulty. Symptoms: Remotes sync but disconnect instantly / never sync / "Communicating with Wii Remote" hangs.
Don't open the Wii unless you're comfortable with ribbon cables and tiny screws. Local retro game shops often charge $40–60 for this repair.