Can Xbox One Games Like Lego Marvel Super Heroes Run on Wii?

No. Xbox One and Wii are fundamentally incompatible platforms.

Why They Don't Work Together

• Architecture: Xbox One uses x86-64 (AMD Jaguar CPU + GCN GPU). Wii uses PowerPC (Broadway CPU + Hollywood GPU). Instruction sets, memory maps, and OS kernels are entirely different.
• Media Format: Xbox One games ship on Blu-ray (or digital). Wii uses proprietary 12 cm DVD-based discs (Wii Optical Disc). Wii drives cannot read Blu-ray; Xbox One drives cannot read Wii discs.
• Software Ecosystem: Xbox One runs a Windows-derived OS (Xbox OS). Wii runs IOS (proprietary microkernel). No emulation layer exists on either.

How to Play Lego Marvel Super Heroes on Nintendo Platforms

• Wii U: Lego Marvel Super Heroes released natively on Wii U (2013). Plays on Wii U or via backward compatibility on Wii U only (not original Wii).
• Nintendo Switch: Lego Marvel Super Heroes 2 (2017) and Lego Marvel Collection (includes 1 & 2) available.
• 3DS: Separate, downgraded version of the first game exists.

If You Only Have a Wii

You cannot play any Xbox One title. Look for Wii-native Lego games: Lego Star Wars: The Complete Saga, Lego Batman 2, Lego City Undercover (Wii U only), Lego Harry Potter Years 1–4 / 5–7.