Metal Slug Anthology on Wii supports only 2-player cooperative play. Four-player mode is not available on this version.
| Version | Max Players | Notes |
|---|---|---|
| Wii (Anthology) | 2 | Wiimote sideways / Classic Controller / GC Controller |
| PS2 (Anthology) | 2 | Same |
| PSP (Anthology) | 2 (Ad-hoc) | Local wireless |
| Neo Geo AES / MVS (Original) | 2 | Cabinet = 2; home = 2 |
| Metal Slug XX (PSP/PS2/360/PC) | 2 | Updated Anthology+ |
| Metal Slug 1-6 (Arcade) | 2 | Original design |
For 4-player Metal Slug, Metal Slug 7 on DS (local wireless) is the only official option. Otherwise, 2-player is the series standard.