Command & Conquer 4: Tiberian Twilight on Xbox 360?

No. Command & Conquer 4: Tiberian Twilight released March 2010 on Microsoft Windows only. No Xbox 360 (or PS3) version was ever produced.

C&C on Consoles

• C&C 3: Tiberium Wars & Kane's Wrath – Xbox 360 (2008).
• Red Alert 3 & Uprising – Xbox 360 / PS3 (2008/2009).
• C&C 4 – PC exclusive (always-online DRM, poorly received).

Play via EA App / Steam on PC. No console port exists.