Can You Play as Gambit in Marvel: Ultimate Alliance (Xbox)?

No. Gambit is not a playable character in the original Marvel: Ultimate Alliance (2006) on Xbox, Xbox 360, PS2, PS3, PSP, Wii, or PC.

When Gambit Became Playable

• Marvel: Ultimate Alliance 2 (2009): Gambit is unlockable (via story progression or challenge). Available on Xbox 360, PS3, Wii, PS2, PSP, PC.
• Marvel Ultimate Alliance 3: The Black Order (2019, Switch): Gambit added via Expansion Pass DLC (Shadow of Doom pack).

Playable X-Men in MUA1 (Xbox/360)

• Wolverine, Storm, Cyclops, Jean Grey, Colossus, Nightcrawler, Iceman, Deadpool (unlockable), Bishop (unlockable).

Mods (PC Only)

The PC version has a massive modding community. Mods like Marvel Mods' "Character Packs" add Gambit, Cable, Psylocke, Magneto, and dozens more with custom powers, skins, and voice lines. Requires Marvel: Ultimate Alliance on Steam/GOG and the Marvel Mods Launcher.

On Xbox consoles, you're limited to the vanilla roster. For Gambit, play MUA2 or MUA3 (Switch).