Deleting a save file permanently erases that character's progress—level, inventory, quest state, position, karma, perks—all gone, irrecoverable on the console. But here's the good news: everything else stays intact.
SAVE####.ESS). Deleting one doesn't touch the others.The Xbox 360 automatically syncs saves to the cloud when signed in to Live (since the 2011 dashboard update). If you delete locally, the cloud copy remains unless you also delete from cloud storage.
Recovery: Settings → System → Storage → Cloud Saved Games → Fallout 3 → Download to Device.
Conflict Resolution: If local ≠ cloud, the console prompts: "Conflict: Keep Local / Keep Cloud / Cancel."
Content/0000000000000000/41560817/00000002/SAVE####.ESS.Bottom Line: Delete with confidence—only the selected character vanishes. Cloud saves are your safety net. Achievements are forever.