Playing Nintendo DS Games on Wii? Impossible Natively. Alternatives.

You cannot play Nintendo DS games on a Wii. Hardware incompatibility:

CPU: Wii (PowerPC Broadway @ 729 MHz) vs DS (ARM9 @ 67 MHz + ARM7 @ 33 MHz). Different ISA.
RAM: Wii 88 MB (24+64) vs DS 4 MB (Phat/Lite) / 16 MB (DSi).
Screens: DS = Dual (Bottom Touch). Wii = Single TV.
Media: DS Card Slot (proprietary) vs Wii Disc / SD.
OS: Bare metal vs IOS. No DS emulator on Wii (insufficient power).

How to Play DS Games on TV / Big Screen

Method	Hardware Needed	Quality	Cost
Nintendo 3DS / 2DS / New 3DS XL	3DS Family + DS Cart / eShop (Closed) / CIA (CFW)	Native, Dual Screen (Top/Bottom), 3D (3DS)	$80–$200 Used
3DS CFW (Luma) + NTR / TWiLight Menu++	3DS + CFW	Boot DS ROMs from SD. Sleep mode works. Cheats.	Free (Time)
melonDS / DeSmuME / RetroArch (PC / Mac / Linux / Android / Steam Deck)	Any Computer	4K, Upscaling, Shaders, Save States, Netplay (Wiimmfi), Fast Forward	Free
Analogue Pocket + DS Adapter (FPGA)	Pocket + $50 Adapter	Cycle-Accurate, 1080p Dock, Original Carts	$260+
Wii U Virtual Console (DS Games)	Wii U + eShop (Closed)	Native Wii U mode, GamePad = Bottom Screen, TV = Top. Only ~20 titles released. Delisted.	N/A (Owned only)
DS Flashcart (R4i Gold 3DS+, EZ-Flash Omega) on 3DS/DSi	Flashcart + 3DS/DSi	Real Hardware, ROMs on microSD, Cheats, Save States	$30–$60

Best All-Around: melonDS on PC/Steam Deck (free, best features) or 3DS with CFW + TWiLight Menu++ (real hardware feel, sleep, streetpass). Wii is a dead end for DS.

Nintendo DS