Can You Connect a Nintendo DS to a Wii? No—Incompatible Platforms

No. The Nintendo DS and Wii are incompatible platforms. You cannot plug a DS cartridge into a Wii, nor does the Wii have hardware/software to run DS code.

Why Not?

• Different Architecture: DS (ARM9/ARM7) vs. Wii (PowerPC).
• Different Media: DS Game Card vs. Wii Optical Disc.
• No Video Input: Wii cannot accept a video signal from a DS.

Playing DS Games on a TV

• Third-Party Capture/Adapter (Hardware): Devices like the "Katsukity" or "Loopy" capture boards install inside a DS/3DS to output HDMI. Expensive, requires soldering/modding.
• Emulation (Software): Play DS roms on a PC/Wii (homebrew) via emulators (DeSmuME, melonDS). Legal only if you own the original cart and dump it yourself.

The intended way to play DS games is on a DS, 3DS, or 2DS family system.