Guitar Hero Controller with The Beatles: Rock Band (Xbox 360)? No—Different Protocols

No. Guitar Hero and Rock Band controllers use different button mappings and protocols. The Xbox 360 only recognizes Rock Band–licensed instruments for Rock Band titles.

• Guitar Hero guitars send different HID reports.
• The Beatles: Rock Band requires a Rock Band guitar, bass, drums, or microphone.
• No adapter or firmware hack makes a GH controller work reliably.

Buy a Rock Band 1/2/3 guitar (or Beatles-branded Hofner bass) for Xbox 360—they're plentiful used and work across all Rock Band games.