Can You Play Wii Games on Xbox 360?

No. Wii games cannot run on Xbox 360. The architectures are fundamentally incompatible.

Why It's Impossible

Component	Wii	Xbox 360
CPU	PowerPC 750CL "Broadway" (729 MHz, single-core, in-order)	PowerPC "Xenon" (3.2 GHz, 3-core, 2-threads each, in-order)
GPU	ATI "Hollywood" (243 MHz, fixed-function TEV pipeline)	ATI "Xenos" (500 MHz, unified shaders, 10 MB eDRAM)
RAM	88 MB (24 MB 1T-SRAM + 64 MB GDDR3)	512 MB GDDR3 (unified)
Media	12 cm Wii Optical Disc (4.7/8.5 GB), proprietary format	DVD-DL (8.5 GB), standard UDF
OS	Broadway IOS (microkernel, per-game)	Xbox 360 OS (NT-based, hypervisor)

No Emulation Path

Xbox 360 is **not powerful enough** to emulate Wii (requires ~3x CPU frequency, different GPU paradigm).
No homebrew emulator exists for Xbox 360 (the 360 homebrew scene is dead; no dev mode for emulators).
Wii discs physically cannot be read by Xbox 360 DVD drive (different groove wobble, encryption, burst cutting area).

How to Play Wii Games Today

Original Wii / Wii U (Backward Compatible): Native, best accuracy. Wii U upscales to 1080p via HDMI.
Dolphin Emulator (PC / Mac / Linux / Android): Gold standard. Runs 99% library at 4K, 60+ FPS, widescreen hacks, HD textures, netplay. Needs decent CPU (i5-6500 / Ryzen 3 3100+).
Nintendo Switch Online + Expansion Pack: Limited selection (N64, GB, GBA, Genesis, NES, SNES — **no Wii games yet**).

If you have Wii discs, a used Wii ($30–$50) + component cable or Wii U ($100–$150) is the easiest legitimate path. For enhanced graphics, Dolphin on a modest PC is superior.

Xbox 360