Playing Game Boy Advance Games on Wii: Not Possible Natively—Use Emulation Instead

You cannot insert a Game Boy Advance cartridge into a Wii. The cartridge slot doesn't exist, the voltage/logic differs, and the Wii's IOS has no GBA hardware abstraction layer.

Why It's Physically & Logically Impossible

• Form factor: GBA cart = 33mm × 54mm edge connector. Wii = 12 cm slot-loading DVD drive. No adapter bridges this.
• Architecture: GBA = ARM7TDMI (16.7 MHz) + custom video/sound. Wii = PowerPC (729 MHz) + ATI GPU. No hardware backward compatibility.
• Software: Wii runs Wii/GC discs. No GBA BIOS, no cartridge reader driver.

How to Play GBA Games on Wii (Homebrew Required)

• VBA GX (Wii homebrew): Full-speed GBA emulator. Load ROMs from SD/USB. Supports saves, cheats, link cable (local multiplayer via two Wiis). Requires Homebrew Channel.
• RetroArch (Wii): mGBA core. Same. More cores (NES, SNES, Genesis, etc.).
• Not64 / Wii64: N64 emulation (bonus).

Better Platforms for GBA

• Original GBA / GBA SP / Game Boy Micro: Authentic. SP AGS-101 (backlit) best.
• Nintendo DS / DS Lite: Native GBA slot. Best official handheld.
• 3DS (Virtual Console / Ambassador / VC injects): Sleep mode, save states, 3D border.
• Analogue Pocket: FPGA hardware accuracy. 1080p docked.
• PC / Phone / Steam Deck: mGBA, RetroArch, Pizza Boy GBA. Free, enhanced.

If you have a Wii, softmod it and run VBA GX for GBA on TV. But for portable, a DS Lite or 3DS is superior. Original hardware > emulation > Wii homebrew for GBA.