Incompatible. The Guitar Hero III PC guitar controller cannot be used with Guitar Hero World Tour on Wii.
| Aspect | GH3 PC Guitar | Wii GHWT Guitar |
|---|---|---|
| Connection | USB (HID class) | Wii Remote expansion port (I2C) or USB dongle (proprietary) |
| Protocol | Standard USB gamepad / XInput | Nintendo-specific encryption + Wii Remote handshake |
| Button Map | 5 frets, strum, whammy, start/back, guide | 5 frets, strum, whammy, +/-, Home, touch strip (slider) |
| Power | USB bus-powered | AA batteries (in Wii Remote) or wired USB (rare) |
If you have the GH3 PC guitar, play Guitar Hero III: Legends of Rock on PC (Steam delisted, but key sites exist) or Clone Hero (free, custom songs, supports almost any USB guitar).
Match the guitar to the console—no cross-platform dongle magic exists.