Can You Play a PS3 Call of Duty Disc on a PC? No – Buy the PC Version

No. PS3 game discs are encrypted Blu-ray media signed for the PS3's Cell processor and proprietary OS. A PC cannot:

• Read the disc format (requires BD drive + PS3-specific firmware).
• Execute PPC/Cell binaries.
• Bypass Sony's DRM (per-disc encryption keys).

Legit Ways to Play Call of Duty on PC

• Buy the PC version (Steam, Battle.net, Microsoft Store).
• CoD: Modern Warfare (2019), MWII, MWIII, BO6, Warzone – native PC.
• Older titles (CoD 4, MW2, BO1, BO2, Ghosts, AW, WWII): On Steam/Battle.net.

Emulation (Not Practical for CoD)

• RPCS3 (PS3 emulator) runs some CoD titles (Black Ops 1, MW2 campaign) but multiplayer dead, heavy CPU needed (8+ cores), frequent bugs.
• Not a viable way to play CoD today.

Buy the PC port. It's cheaper, runs better, has active players, mod support, and KB/M or controller.