Is Creed: Brotherhood Available on Wii?

No. Assassin's Creed: Brotherhood (2010) was released on:

• PlayStation 3
• Xbox 360
• Microsoft Windows
• Mac OS X (via Steam)

The Wii's hardware (single-core Broadway CPU, 88 MB RAM, fixed-function GPU) couldn't run the Anvil engine. Ubisoft released Assassin's Creed: Bloodlines (PSP) and Assassin's Creed II: Discovery (DS/iOS) as handheld alternatives instead.

Wii Boxing Alternatives

• Fight Night Round 4 (2009) – Best sim boxing on Wii; uses MotionPlus for 1:1 punching.
• EA Sports Fight Night Champion (2011) – Not on Wii (PS3/360 only).
• Punch-Out!! (2009) – Arcade-style, pattern-based, excellent MotionPlus support.
• The Bigs 2 (2009) – Baseball, but similar "swing" mechanics.

For Assassin's Creed on Nintendo hardware, the series debuted on Switch with The Ezio Collection (2022) and Valhalla (cloud version).