Wii Game Compatibility with GameCube: One-Way Only

No. Wii games do not work on GameCube.

• Hardware: Different CPU, memory, and disc drive.
• Disc Format: Wii uses standard DVD-R; GameCube uses proprietary mini-DVD.
• Backward Compatibility: Wii plays GameCube games (with GC controller and memory card), but not vice versa.

You can play GameCube games on a Wii, but never Wii games on a GameCube.