Short answer: No. A UK (PAL region) PlayStation 2 game will not run on a US (NTSC-U/C region) PlayStation 3. The compatibility barrier is hard-coded into the system.
ps2_netemu configuration or by converting the game to a "PS2 Classics Placeholder" format. Compatibility is hit-or-miss and not guaranteed for every title.Good to know: PlayStation 3 games are region-free (with the rare exceptions of Persona 4 Arena and Way of the Samurai 3). PlayStation 1 games on PS3 remain region-locked. DVD and Blu-ray movies follow their own standard region coding.